heres how u do it. find a plex 3/10 serp plex they are in high and low sec(see below for a short list).
farm the keys u need to get some keys they drop from:
1st stage: Traffic Management (structure. drops trafic management passkey)
2nd stage a:chief of security (cruiser right hand gate.drops security corridor pass)
b:Staff Quarters (structure left hand gate. drops serpentes staff passkey)
3rd stage Serpentes Headmaster (cruiser)
all also drop loot sometimes its shit, sometimes its faction (best u can get is serpentes tracking computers and mag stabs.)
do the plex or if their is others near do them aswell. collect the keys you will need a supply of them if u want to make isk.
IMPОRTANT: do not go into last stagе (stage 4) serpentes administration i think its called. Its the stage after the stage u get the headmaster in.
Their is nothing in the last stage except when the stronghold spawns no ships here drop loot worth a toss. just farm the keys and overseers effects.
ok so u got a bunch of keys 3 of each should be fine for a bit. You need to know ure spawntimes for the stronghold. these spawn straight after downtime and then 8 hours after it gets blown up so u have 3 spawns a day. one about 12 eve time 1 about 8pm and 1 at about 4 am.
possable loot in stronghold:
gistii a-type small shield booster‚
gistii a-type 1mn microwarpdrive
gistii a-type 1mn afterburner
gistii a-type small shield transporter
various named stuff and serpentes guns domination stuff also spawns VERY rare though
daredevil 1 run bpc
what u get is random u may ger only a 9th tier overseers effects (2.1 mill isk) or u may hit the jackpot and get it ALL ( 180mill ish from one drop)
TIPS:
For respawns fit dome dps its the highest damage that gets rights on the can. but remember they can still steal it!! so u can fit for pvp if u want.
for downtime spawn fit speed speed and more speed!!! 1000+ms is a must, vagabond is recomended as its a race to the finish to kill the stronghold. i can do 2200ms in my vaga and it seems to do the trick nice. i can get to the end and kill it b4 most people get into the last but with me.
Fit a tractor beam.
you can tank the rats in here in a cruiser fit for kin and therm damage. a hac/recon is recomended as competion can be stiff.
In the last stage be there 10-15 mins b4 the stronghold re-spawns so u can kill off the frigs as they still re-spawn in here.
Sit 15km behind the middle cargo can in the last stage to be 4000m from the structure when it spawns. and if someone's trying to get smart and is sitting where the can drops (caracal/vexor are likely to do this becuse they dont have to be at optimals) just charge them as the structure gets to 85-90% structure and bump them through the thing they will get thrown a good 8000m off the can that drops.
Lock them this will often be enough to discourage chineese farmers from looting ure can, and if u want, try to get them to take it if u can scram them as if u kill one(its difficult to get a scram and a lock with the lag as the structure explodes) they do have nice mods on the ship.
i scanned down a navy caracal once it had: gistii small shield booster, 10mn dominaton afterdurner all t2 heavies domnation overdrive injectors and a dread guristas bcu!!! (he wont loot my can)

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you can make good isk doing this with an alt i can make 1/2 a billion a week easy,
for low skill and alts. all that is really needed is a caracal and some practice but the better the ship the easier it is.
There is nothin better than stealin the can of a farmer iwith a caracal. the chinese abuse in local is hilarious.
just fit some stabs incase he has a scram (doubtfull though) and sit right where the can drops, ninja loot it and fly off. hehe
SYSTEMS WITH PLEXES.
HIGH SEC:
Leremblompes,
torvi,
vaurient,
junsoraert,
chantarouse (there is a plexer here called maphell he is bloody good u wont be able to beat him in the plex),
boilair
arnon
nibale
weraroix
vilinon
LОW SEC:
agozе
ostingele
manar
kenninck
aulbres
there are others these are the ones i can think of off the top of my head.
if u have any questions ask me ingame or here.
happy farming
ps plz dont do aydoteaux as its the one i run and its difficult enough with the 2 chineese farmers there already lol.